The world blew out in 2001. Vast areas of what was the United States lie beneath an umbrella of noxious dust and radioactive debris, a mantle of destruction drawn over a land of doom. Much of the East Coast has been obliterated; the Southwest is a land of fire; cities of smoldering ash have given birth to horrifically mutated life forms. Such is the Deathlands, legacy of global annihilation.

But there were survivors, struggling to overcome a dark new age of plague, radiation sickness, barbarism and madness. Out of the ruins come Ryan Cawdor and his band of post-holocaust survivors, whose odyssey of discovery takes them in search of other pockets of civilization.